1. Nicola Minali (Italy) Gewiss 5.34.38 2. Steffen Wesemann (Germany) Telekom 3. Sergei Smetanin (Russia) Santa Clara 4. Marcel Wust (Germany) MX Onda 5. Tom Steels (Belgium) Mapei 6. Biagio Conte (Italy) Scrigno 7. Martin Hvastija (Slovenia) Cantina 8. Paolo Valoti (Italy) Cantina 9. Denis Zanette (Italy) AKI 10. Marco di Renzo (Italy) Cantina 11. Giuseppe Citterio (Italy) AKI 12. Laurent Jalabert (France) ONCE 13. Pascal Chanteur (France) Petit Casino 14. Mauro Gianetti (Switzerland) Polti 15. Bobby Julich (U.S.) Motorola 16. Laurent Dufaux (Switzerland) Lotus 17. Juergen Werner (Germany) Telekom 18. Jose Espinosa (Spain) MX Onda 19. Angel Edo (Spain) Kelme 20. Inaki Aiarzaguena (Spain) Euskadi all same time
1. Alex Zuelle (Switzerland) ONCE 72.32.19 2. Laurent Jalabert (France) ONCE 1.23 3. Dufaux 5:26 4. Roberto Pistore (Italy) MG 7:14 5. Stefano Faustini (Italy) AKI 7:22 6. Davide Rebellin (Italy) Polti 7:55 7. Georg Tostching (Austria) Polti 8:36 8. Melchor Mauri (Spain) ONCE 8:45 9. Tony Rominger (Switzerland) Mapei 8:55 10. Neil Stephens (Australia) ONCE 9:20 11. Julich 11:00 12. Andrea Peron (Italy) Motorola 12:37 13. Mikel Zarrabeitia (Spain) ONCE 13:55 14. Daniel Clavero (Spain) MX Onda 14:34 15. Massimo Apollonio (Italy) Scrigno 14:45 16. Vladislav Bobrik (Russia) Gewiss 15:05 17. Fernando Escartin (Spain) Kelme 15:20 18. Marcos Serrano (Spain) Kelme 15:28 19. Jose Maria Jimenez (Spain) Banesto 15:50 20. Mauro Gianetti (Switzerland) Polti 16:06
But Swiss Alex Zuelle maintained overall supremacy heading into the final week, one minute ahead of ONCE team mate Laurent Jalabert of France.
After four days of mountain finishes, the riders were able to relax and made the best of good weather and tail winds on the 222 km haul from Logrono to Sabinanigo.
Minali timed his break to the line well and finished stage 16 with a comfortable advantage over Germany's Steffen Wesemann and Russian Sergei Smetanine.
The 158 km haul from Sabinanigo to the tough mountain finish at Celer on Tuesday appears to be the last real chance for anyone to catch Zuelle and Jalabert before the Tour ends in Madrid on Sunday.
Switzerland's Alex Zulle, second in the 1993 Tour, retained the overall leader's yellow jersey.
Minali, the 1995 Paris-Tours Classic winner, beat Germany's Stefan Wesemann and Tom Steels of Belgium in a sprint finish.
Although Christophe Agnolutto of France, Spaniard Alvaro Gonzalez de Galdeano and Angelo Canonzieri of Italy escaped after 167km they were reeled in after only 40km.
Veteran Italian Gianni Bugno, a former double world champion, also escaped with 15km to the finish but the peloton caught him and Minali celebrated yet another triumph.
Minali, though, will find Tuesday's stage less to his liking as the Tour enters the Pyrennees
Jalabert, who lies second overall behind Swiss teammate Alex Zulle, complained that the race, which he won last year, had become too difficult.
"This Tour has become too hard. We have had a lot of difficult days and the weather hasn't been too good. The peloton has also ridden extremely fast and everybody is exhausted," Jalabert said.
Spanish cyclist Angel Edo was franker about how he felt.
"I am dead. This race really shouldn't come at the end of September, as we're all exhausted after the Tour of Italy and the Tour de France," Edo said.
Meanwhile Italian cyclist Nicola Minali won his fourth stage taking the 220.9km 16th stage, the Tour's longest, from Logrono to Sabinanigo -- bettering his 1995 Tour performance when he won three stages.
Minali, the 1995 Paris-Tours Classic winner, beat Germany's Stefan Wesemann and the Russian Sergei Smetanine in a sprint finish.
Germany's Marcel Wust, who finished fourth in the stage, said he was another who was really suffering.
"I can't even speak. I am going to find it very hard to finish in Madrid on September 29," Wust said.
Although Christophe Agnolutto of France, Spaniard Alvaro Gonzalez de Galdeano and Angelo Canonzieri of Italy escaped after 167km they were reeled in after only 40km.
Veteran Italian Gianni Bugno, a former double world champion, also escaped with 15km to the finish but the peloton caught him and Minali celebrated yet another triumph.
Tuesday's 17th stage is a 165.7km ride into the Pyrennees from Sabinanigo to the summit of Alto d'Ampriu, a climb so high at 1,930m that its not categorised.
There are two other significant climbs, the first category Alto de Cotefablo and the second category De La Forada.